
These nanoparticles are produced by the incomplete combustion of the cigarettes. have shown that this black substance is made of nano-sized particles of a material called carbon black (which is also known as elemental carbon). Now, by studying lung tissue taken from smokers with emphysema, You et al. Previously, little was known about the composition of the substance that causes this blackening, or its significance in the development of emphysema. One of the hallmarks of long-term smoking is a blackening of the lung tissue that persists even if someone stops smoking. Moreover, cigarette smoke also contains large numbers of small particles and relatively little is known about the role played by these particles in smoking-related disease. There are thousands of chemicals in cigarette smoke and many of them have been linked to the development of lung cancer, although it has been difficult to pinpoint those that are responsible for smoking-related emphysema. Smoking for many years damages the lungs and leads to a disease called emphysema that makes it difficult to breathe and is often deadly. Thus, nCB causes sterile inflammation, DSB, and emphysema and explains adverse health outcomes seen in smokers while implicating the dangers of nCB exposure in non-smokers. Increasing the polarity or size of CB mitigated many adverse effects. Delivered by smoking or intranasally, nCB persisted indefinitely in mouse lung, activated lung APCs, and promoted T helper 17 cell differentiation through double-stranded DNA break (DSB) and ASC-mediated inflammasome assembly in phagocytes. Likewise, nCB intranasal administration induced emphysema in mouse lungs. In this study, we show that insoluble nanoparticulate carbon black (nCB) accumulates in human myeloid dendritic cells (mDCs) from emphysematous lung and in CD11c + lung antigen presenting cells (APC) of mice exposed to smoke. The effect of carbon black (CB), a universal constituent of smoke derived from the incomplete combustion of organic material, in smokers and non-smokers is less known.


Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Abandoned Application number US13/128,871 Inventor Marianna Foldvari Original Assignee Marianna Foldvari Priority date (The priority date is an assumption and is not a legal conclusion.
#Carbon black dispersio in water tween pdf
Google Patents Dispersion and debundling of carbon nanotubes using gemini surfactant compoundsĭownload PDF Info Publication number US20110300126A1 US20110300126A1 US13/128,871 US200913128871A US2011300126A1 US 20110300126 A1 US20110300126 A1 US 20110300126A1 US 200913128871 A US200913128871 A US 200913128871A US 2011300126 A1 US2011300126 A1 US 2011300126A1 Authority US United States Prior art keywords carbon nanotubes dispersion gemini surfactant gemini nanotubes Prior art date Legal status (The legal status is an assumption and is not a legal conclusion. Google Patents US20110300126A1 - Dispersion and debundling of carbon nanotubes using gemini surfactant compounds US20110300126A1 - Dispersion and debundling of carbon nanotubes using gemini surfactant compounds
